Not surprisingly, Luc Barvais from the Erasme University in Bruxelles was the initiator of the development of a local Target Controlled Infusion (TCI) system. He made a major contribution to the teaching of TCI with the very frequently cited and downloaded publication. We encourage you to take notice from this downloadable publication.
From TCI Luc went on to other interesting aspects connected to intravenous anaesthesia: measuring the analgesic component of IV anaesthesia. You can here download a yet unpublished manuscript on the Nociception-Antinociception balance.
The clinical evaluation and validation of the Nociception Level Index was done in the following publication.
Some further enlightments on the topic can be downloaded here where the effect of Dexmedetomidine on the requirements for remifentanil and propofol is investigated using the Nociception Level Index
Possibly the next development in anaesthesia for the next decade is the development of closeloop anaesthesia. The team at the Erasme Hospital from the Universite Libre in Bruxelles in cooperation with partners made recently some major progress in that direction as you can see in these downloadable publications.