In the pharmacokineticsDiY part 1 the numerical approach of pharmacokinetic calculations was explained. Using relative simple formulas implemented in a spreadsheet the concentrations of a drug could be calculated following variable drug input protocols. The Eleveld model for propofol was used. This was not without a reason. Douglas Eleveld and…
part 1:building and verifying the spreadsheet This blog is about pharmacokinetics: Do It Yourself. Only a bit of knowledge of using spreadsheets is required. If you read publications on pharmacokinetics you will have noticed that the model parameters are usually presented in two different notations: clearances V1,V2,V3,…
My name is Stefan Schraag. Since 2008 I have been chairing the Board of EuroSIVA, a handpicked selection of experts in the field of clinical pharmacology, research and monitoring. Together, we have achieved to establish a team of expertise in many areas of intravenous anaesthesia and target-controlled infusion (TCI). Over…
Using my prerogative as webmaster I open this blog to inform you on the purpose and features of the blog. In the Eurosiva-blog the individual board members will write what keeps them busy or what they think is interesting for IV and not so IV enthusiast colleagues. We plan to…